Iodine-mediated guanidine formation through arylsulfonyl-activated thioureas
Reaction of arylsulfonyl thioureas with amines to form guanidines can be efficiently promoted through the use of iodine, instead of conventional reagents such as the Mukaiyama reagent or EDC. The general scope and limitations of the reaction are probed.
Qin, Cuiying,Li, Jizhen,Fan, Erkang
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p. 2465 - 2468
(2010/01/16)
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