Amnesia-reversal activity of a series of 5-alkoxy-1-arylcarbonyl-2-pyrrolidinones and 5-alkoxy-1-arylmethyl-2-pyrrolidinones
A series of 5-alkoxy-1-arylcarbonyl-2-pyrrolidinones (1-27) were prepared by condensation of arylcarbonyl chlorides with 5-alkoxy-2-pyrrolidinones in the presence of butyl lithium in tetrahydrofuran.Alkylation of these intermediates with substituted benzy
Toja, E,Gorini, C,Zirotti, C,Barzaghi, F,Galliani, G
p. 415 - 422
(2007/10/02)
Derivatives of 1-benzyl-2-oxo-5-alkoxy-pyrrolidine, and medicament compositions containing them
Compounds useful in the treatment of patients suffering from intellectual or nervous asthenias, memory failures, senescence or metal strain of the formula (I) STR1 in which R' represents hydrogen, linear, branched or cyclic alkyl containing up to 12 carbo
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(2008/06/13)
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