Construction of 5,6-ring-fused 2-pyridones: An effective annulation tactic achieved in water
An efficient protocol to annulate the 5,6-fused 2-pyridone ring system, exploiting a tandem condensation of propiol-amide and cyclic -keto methyl esters in water, followed by acid- or base-promoted intramolecular ring closure and decarboxylation, has been
Smith III, Amos B.,Atasoylu, Onur,Beshoreb, Douglas C.
experimental part
p. 2643 - 2646
(2010/01/16)
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