Synthesis and conformational analysis of a novel carbohydrate-fused bis-crown ether: crown-CyPLOS
A novel sugar-based macrocycle consisting of a phosphate-linked 12-membered disaccharide ring (cyclic phosphate-linked oligosaccharide, CyPLOS), fused to two 18-crown-6 ether residues, is here described. The synthesis of the target compound has been accom