1,2-Diamines as inhibitors of co-activator associated arginine methyltransferase 1 (CARM1)
We have identified the N1-benzyl-N2-methylethane-1,2-diamine unit as a substitute for the (S)-alanine benzylamide moiety for the design of co-activator associated arginine methyltransferase 1 (CARM1) inhibitors. The potency of these