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2-Propen-1-ol, 3-(3-pyridinyl)-, (2E)-(9CI), also known as 3-vinylpyridine, is an unsaturated alcohol with the molecular formula C8H9NO. It is a versatile chemical compound that finds applications in various industries due to its unique properties.

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  • 120277-39-6 Structure
  • Basic information

    1. Product Name: 2-Propen-1-ol,3-(3-pyridinyl)-,(2E)-(9CI)
    2. Synonyms: 2-Propen-1-ol,3-(3-pyridinyl)-,(2E)-(9CI)
    3. CAS NO:120277-39-6
    4. Molecular Formula: C8H9NO
    5. Molecular Weight: 135.16
    6. EINECS: N/A
    7. Product Categories: PYRIDINE
    8. Mol File: 120277-39-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: Inert atmosphere,Room Temperature
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-Propen-1-ol,3-(3-pyridinyl)-,(2E)-(9CI)(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-Propen-1-ol,3-(3-pyridinyl)-,(2E)-(9CI)(120277-39-6)
    11. EPA Substance Registry System: 2-Propen-1-ol,3-(3-pyridinyl)-,(2E)-(9CI)(120277-39-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 120277-39-6(Hazardous Substances Data)

120277-39-6 Usage

Uses

Used in Pharmaceutical Industry:
2-Propen-1-ol, 3-(3-pyridinyl)-, (2E)-(9CI) is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows it to be a key component in the development of new drugs, contributing to the advancement of medicine.
Used in Chemical Synthesis:
2-Propen-1-ol,3-(3-pyridinyl)-,(2E)-(9CI) serves as a reagent in organic synthesis, enabling the creation of a wide range of chemical compounds. Its versatility in chemical reactions makes it a valuable asset in the field of chemistry.
Used in Surfactant and Polymer Production:
2-Propen-1-ol, 3-(3-pyridinyl)-, (2E)-(9CI) is utilized as a raw material in the manufacturing of surfactants and polymers. Its properties contribute to the development of these materials, enhancing their performance and expanding their applications.
Used in Flavors and Fragrances Industry:
This versatile chemical is also employed in the production of flavors and fragrances, adding unique scents and tastes to various products. Its use in this industry highlights its ability to enhance the sensory experience of consumers.

Check Digit Verification of cas no

The CAS Registry Mumber 120277-39-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,0,2,7 and 7 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 120277-39:
(8*1)+(7*2)+(6*0)+(5*2)+(4*7)+(3*7)+(2*3)+(1*9)=96
96 % 10 = 6
So 120277-39-6 is a valid CAS Registry Number.

120277-39-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name (2E)-3-(3-Pyridinyl)-2-propen-1-ol

1.2 Other means of identification

Product number -
Other names 3-Pyridin-2-ylacrolein

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:120277-39-6 SDS

120277-39-6Relevant articles and documents

Photoredox Activation of SF6for Fluorination

McTeague, T. Andrew,Jamison, Timothy F.

supporting information, p. 15072 - 15075 (2016/11/25)

We report the first practical use of SF6as a fluorinating reagent in organic synthesis. Photoredox catalysis enables the in situ conversion of SF6, an inert gas, into an active fluorinating species by using visible light. Under these conditions, deoxyfluorination of allylic alcohols is effected with high chemoselectivity and is tolerant of a wide range of functional groups. Application of the methodology in a continuous-flow setup achieves comparable yields to those obtained with a batch setup, while providing drastically increased material throughput of valuable allylic fluoride products.

Silylative cyclopropanation of allyl phosphates with silylboronates

Shintani, Ryo,Fujie, Ryuhei,Takeda, Momotaro,Nozaki, Kyoko

supporting information, p. 6546 - 6549 (2014/06/24)

A potassium-bis(trimethylsilyl)amide-mediated cyclopropanation of allyl phosphates with silylboronates has been developed. Unlike the reported copper-catalyzed allylic substitution reactions, the nucleophile selectively attacks at the β-position of the allylic substrates under the present reaction conditions. The mechanism of this process has also been investigated, thus indicating the involvement of a silylpotassium species as the active nucleophilic component.

Pd-catalyzed enantioselective allyl-allyl cross-coupling

Zhang, Ping,Brozek, Laura A.,Morken, James P.

supporting information; scheme or table, p. 10686 - 10688 (2010/11/04)

The Pd-catalyzed cross-coupling of allylic carbonates and allylB(pin) is described. The regioselectivity of this reaction is sensitive to the bite angle of the ligand, with small-bite-angle ligands favoring the branched substitution product. This mode of

Enantioselective synthesis of (+)(R)- And (-)(S)-nicotine based on Ir-catalysed allylic amination

Welter, Carolin,Moreno, Rosa M.,Streiff, Stephane,Helmchen, Guenter

, p. 3266 - 3268 (2007/10/03)

The synthesis of nicotine with enantiomeric excess of >99% ee was accomplished by asymmetric Ir-catalysed allylic amination followed by ring closing metathesis and racemisation-free double bond reduction. The Royal Society of Chemistry 2005.

3-Descladinosyl-6-O-carbamoyl and 6-O-carbonoyl macrolide antibacterial agents

-

Page/Page column 57-58, (2010/02/05)

3-Descladinosyl-6-O-carbamoyl and 6-O-carbonoyl macrolide antibacterial agents of the formula: wherein R1, W, R3, R4, R5, R6, X, X′, and Z are as described herein and in which the substituents have th

AROYL-PIPERAZINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS TACHYKININ ANTAGONISTS

-

, (2008/06/13)

This invention relates to piperazine derivatives of formula (I), wherein Y is bond or lower alkylene, R1 is aryl which may have substituent(s), R2 is aryl or indolyl, each of which may have substituent(s), R3 is hydrogen or lower alkyl, and R4 is as defined in the description, and its pharmaceutically acceptable salt, to processes for preparation thereof, to pharmaceutical composition comprising the same, and to a use of the same for treating or preventing Tachykinin-mediated diseases in human beings or animals. 1

Synthesis and antifungal activities of R-102557 and related dioxane- triazole derivatives

Oida, Sadao,Tajima, Yawara,Konosu, Toshiyuki,Nakamura, Yoshie,Somada, Atsushi,Tanaka, Teruo,Habuki, Shinobu,Harasaki, Tamako,Kamai, Yasuki,Fukuoka, Takashi,Ohya, Satoshi,Yasuda, Hiroshi

, p. 694 - 707 (2007/10/03)

Novel triazole compounds with a dioxane ring were synthesized. Condensation of the diol precursor 10 with various aromatic aldehydes 11 - 13 under acidic conditions afforded a series of dioxane-triazole compounds 14 - 16. The antifungal activities of the compounds 14 - 16 were evaluated in vivo in mice infection models against Candida and Aspergillus species. High activities were seen for the derivatives with one or two double bond(s) and an aromatic ring substituted with an electron-withdrawing group in the side chain. Among the derivatives, R-102557 (16R: Ar=4-(2,2,3,3- tetrafluoropropoxy)phenyl) showed excellent in vivo activities against Candida, Aspergillus and Cryptococcus species. It also showed high tolerance in a preliminary toxicity study in rats.

Synthesis and anti-HIV activity of novel N-1 side chain-modified analogs of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT)

Pontikis, Renée,Benhida, Rachid,Aubertin, Anne-Marie,Grierson, David S.,Monneret, Claude

, p. 1845 - 1854 (2007/10/03)

A series of 33 N-1 side chain-modified analogs of 1-[(2- hydroxyethoxy)methyl]-6-(phenylthio)thymine (1, HEPT) were synthesized and evaluated for their anti-HIV-1 activity. In particular, the influence of substitution of the terminal hydroxy group of the acyclic structure of HEPT and the structural rigidity of this side chain were investigated. Halo (7, 8), azido (9), and amino (10-15) derivatives were synthesized from HEPT via the p-tosylate derivative 6. Acylation of the primary amine 15 afforded the amido analogs 16-20. The diaryl derivatives 26-29 were prepared by reaction of HEPT, or of the 6-(2-pyridylthio) analog 23, with diaryl disulfides in the presence of tri-n-butylphosphine. Compounds 39-41, in which the N-1 side chain is rigidified by incorporation of an E-configured double bond, were obtained by palladium(0)-catalyzed coupling of several different 6- (arylthio)uracil derivatives (37, 38) with allyl acetates 33. Compounds 13, 40a,c,d,f, and 41, incorporating an aromatic ring at the end of the acyclic side chain, were found to be more potent than the known diphenyl-substituted HEPT analog BPT (2), two of them, 40c,d, being 10-fold more active.

Synthesis of the anthraquinone part of dynemicin a via Diels-Alder reaction

Nishikawa, Toshio,Moku, Masatoshi,Suzuki, Yoko,Isobe, Minoru

, p. 113 - 114 (2007/10/03)

The anthraquinone moiety of dynemicin A was synthesized by Diels-Alder reaction between bromonaphthoquinone and a novel diene having the D ring and aromatization as key steps.

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