1202810-70-5Relevant articles and documents
Imidazo[1,2-a]pyrazine diaryl ureas: Inhibitors of the receptor tyrosine kinase EphB4
Mitchell, Scott A.,Danca, Mihaela Diana,Blomgren, Peter A.,Darrow, James W.,Currie, Kevin S.,Kropf, Jeffrey E.,Lee, Seung H.,Gallion, Steven L.,Xiong, Jin-Ming,Pippin, Douglas A.,DeSimone, Robert W.,Brittelli, David R.,Eustice, David C.,Bourret, Aaron,Hill-Drzewi, Melissa,Maciejewski, Patricia M.,Elkin, Lisa L.
experimental part, p. 6991 - 6995 (2010/07/15)
Inhibition of receptor tyrosine kinases (RTKs) such as vascular endothelial growth factor receptors (VEGFRs) and platelet-derived growth factor receptors (PDGFRs) has been validated by recently launched small molecules Sutent and Nexavar/