USE OF INTERPHASE CATALYSIS IN THE SYNTHESIS OF 2-ACYL-4-OXOPYRAZINOISOQUINOLINES AND 4-ACYL-2-PIPERAZINONES
2-acetyl-4-oxopyrazinoisoquinolines and 4-acyl-2-piperazinones have been synthesized, with interphase catalysis, by the intramolecular N-alkylation of the corresponding diamides.
Sergovskaya, N. L.,Chernyak, S. A.,Shekhter, O. V.,Tsizin, Yu. S.
p. 888 - 891
(2007/10/02)
SYNTHESIS OF 2-CYCLOHEXYLCARBONYL-4-OXOPERHYDROPYRAZINOISOQUINOLINE
2-Cyclohexylcarbonyl-4-oxoperhydropyrazinoisoquinoline, an analog of the highly effective anthelmintic prasiquantel, was synthesized from 2-(cyclohexen-1-yl)-ethylamine.
Tsizin, Yu. S.,Sergovskaya, N. L.,Shekhter, O. V.
p. 920 - 922
(2007/10/02)
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