- Tetrahydrothiadiazoloisoquinolines: Synthesis and inhibition of phenylethanolamine-N-methyltransferase
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A series of 7,8-fused heterocyclic tetrahydroisoquinolines were synthesized and tested as inhibitors of rabbit adrenal phenylethanolamine-N-methyltransferase (PNMT). 6,7,8,9-Tetrahydro[1,2,3]thiadiazolo[5,4-h]isoquinoline 5 (SK and F 86607) was found to b
- Girard,Bondinell,Hillegass,Holden,Pendleton,Uzinskas
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p. 1566 - 1571
(2007/10/02)
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