Reductive Aromatization of Quinols with B2pin2 as Deoxidizing Agent
We have demonstrated B2pin2 as superior deoxidizing agent for the reductive deoxygenation of quinol derivatives under basic conditions. A wide range of highly functionalized phenols were obtained in good yields including a complex drug molecule, which revealed the high functional group tolerance of this protocol.
Liu, Bin,Xu, Yin,Luo, Zhibin,Xie, Jimin
supporting information
p. 1022 - 1024
(2020/03/19)
Strategic Approach on N-Oxides in Gold Catalysis – A Case Study
An extensive kinetic study of selected key reactions of (oxidative) gold catalysis concentrates on the decrease of the catalytic activity due to inhibition of the gold(I) catalyst caused by pyridine derivatives that are obtained as by-products if N-oxides are applied as oxygen donors. The choice of the examined pyridine derivatives and their corresponding N-oxides has been made regardless of their commercial availability; particular attention has been paid to the practical benefit which up to now has been neglected in most of the reaction screenings. The test reactions were monitored by GC and 1H NMR spectroscopy. The received reaction constants provide information concerning a correlation between the electronic structure of the heterocycle and the catalytic activity. Based on the collected kinetic data, it was possible to develop a basic set of three N-oxides which have to be taken into account in further oxidative gold(I)-catalyzed reactions. (Figure presented.).
Schie?l, Jasmin,Stein, Philipp M.,Stirn, Judith,Emler, Kirsten,Rudolph, Matthias,Rominger, Frank,Hashmi, A. Stephen K.
supporting information
p. 725 - 738
(2018/10/20)
Gold-Catalyzed Synthesis of Tropone and Its Analogues via Oxidative Ring Expansion of Alkynyl Quinols
A new and convenient strategy for the synthesis of functionalized tropone derivatives based on the gold-catalyzed oxidative ring expansion of alkynyl quinols has been developed. The reaction proceeds via gold-catalyzed highly regioselective oxidation foll
A direct approach to 5-hydroxybenzofurans via a platinum-catalyzed domino rearrangement/5-endo-dig cyclization reaction of quinols
(Chemical Equation Presented) A highly efficient and atom-economical construction of 2-substituted 5-hydroxybenzofurans was accomplished by employing a platinum-catalyzed domino dienone-phenol rearrangement/5-endo-dig cyclization reaction of quinols beari
Kim, Ikyon,Kim, Kyungsun,Choi, Jungeun
supporting information; experimental part
p. 8492 - 8495
(2010/03/01)
Ligand Assisted Nucleophilic Additions. Control of Site and Face Attack of Nucleophiles on 4-Oxidoenones
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Solomon, Mark,Jamison, W. Charles L.,McCormick, Michael,Liotta, Dennis,Cherry, David A.,et al.
p. 3702 - 3704
(2007/10/02)
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