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LY 2801653 dihydrochloride, also known as N-[3-Fluoro-4-[[1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl]oxyphenyl]-1-(4-fluorophenyl)-6-methyl-2-oxopyridine-3-carboxamide dihydrochloride, is a chemical compound with potential applications in the pharmaceutical industry. It is characterized by its unique molecular structure and properties, making it a promising candidate for the development of new drugs and therapeutic agents.

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  • N-[3-fluoro-4-[1-methyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxyphenyl]-1-(4-fluorophenyl)-6-methyl-2-oxopyridine-3-carboxamide,dihydrochloride

    Cas No: 1206801-37-7

  • USD $ 1.9-2.9 / Gram

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  • 1206801-37-7 Structure
  • Basic information

    1. Product Name: LY 2801653 dihydrochloride
    2. Synonyms: LY 2801653 dihydrochloride;LY2801653 (dihydrochloride);LY-2801653 dihydrochloride;N-[3-Fluoro-4-[[1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl]oxy]phenyl]-1-(4-fluorophenyl)-1,2-dihydro-6-methyl-2-oxo-3-pyridinecarboxamide hydrochloride (1:2);LY2801653 2HCl
    3. CAS NO:1206801-37-7
    4. Molecular Formula: C30H24Cl2F2N6O3
    5. Molecular Weight: 625.4527664
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1206801-37-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: LY 2801653 dihydrochloride(CAS DataBase Reference)
    10. NIST Chemistry Reference: LY 2801653 dihydrochloride(1206801-37-7)
    11. EPA Substance Registry System: LY 2801653 dihydrochloride(1206801-37-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1206801-37-7(Hazardous Substances Data)

1206801-37-7 Usage

Uses

Used in Pharmaceutical Industry:
LY 2801653 dihydrochloride is used as a reactant/reagent in the synthetic preparation of amidophenoxyindazoles, which are inhibitors of c-Met. These amidophenoxyindazoles have potential applications in the treatment of various diseases, including cancer, by targeting the c-Met receptor and modulating its activity.
In the development of new drugs and therapeutic agents, LY 2801653 dihydrochloride plays a crucial role as a building block in the synthesis of amidophenoxyindazoles. These compounds have shown promising results in inhibiting the c-Met receptor, which is involved in various cellular processes and has been implicated in the progression of several diseases, particularly cancer. By targeting the c-Met receptor, amidophenoxyindazoles have the potential to offer novel treatment options for patients suffering from these conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 1206801-37-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,0,6,8,0 and 1 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1206801-37:
(9*1)+(8*2)+(7*0)+(6*6)+(5*8)+(4*0)+(3*1)+(2*3)+(1*7)=117
117 % 10 = 7
So 1206801-37-7 is a valid CAS Registry Number.

1206801-37-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name N-[3-fluoro-4-[1-methyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxyphenyl]-1-(4-fluorophenyl)-6-methyl-2-oxopyridine-3-carboxamide,dihydrochloride

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:1206801-37-7 SDS

1206801-37-7Relevant articles and documents

AMIDOPHENOXYINDAZOLES USEFUL AS INHIBITORS OF C-MET

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Page/Page column 19, (2010/02/17)

The present invention provides amidophenoxyindazole compounds useful in the treatment of cancer.

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