1206968-88-8

Basic information

• Product Name: (5-Bromo-3-chloropyridin-2-yl)methanol
• Synonyms: (5-Bromo-3-chloropyridin-2-yl)methanol
• CAS NO: 1206968-88-8
• Molecular Formula: C₆H₅BrClNO
• Molecular Weight: 222.467
• Mol File: 1206968-88-8.mol

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: (5-Bromo-3-chloropyridin-2-yl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (5-Bromo-3-chloropyridin-2-yl)methanol(1206968-88-8)
• EPA Substance Registry System: (5-Bromo-3-chloropyridin-2-yl)methanol(1206968-88-8)

Safety Data

• Hazardous Substances Data: 1206968-88-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(5-Bromo-3-chloropyridin-2-yl)methanol is used as a key intermediate in the synthesis of pharmaceutical compounds for various therapeutic applications. Its unique structure and halogenated nature allow for the development of novel drugs with specific biological activities and improved pharmacokinetic properties.
Used in Agrochemical Industry:
In the agrochemical industry, (5-Bromo-3-chloropyridin-2-yl)methanol serves as a crucial building block for the creation of new agrochemicals, such as pesticides and herbicides. Its halogenated pyridine structure can be tailored to target specific pests or weeds, enhancing the effectiveness and selectivity of these agrochemicals.
Used in Organic Synthesis:
(5-Bromo-3-chloropyridin-2-yl)methanol is utilized as a versatile intermediate in organic synthesis, allowing for the preparation of a wide range of functionalized pyridine derivatives. Its reactivity and structural diversity make it an attractive candidate for the development of new organic compounds with potential applications in various fields, such as materials science, catalysis, and medicinal chemistry.
Used in Research and Development:
In research and development, (5-Bromo-3-chloropyridin-2-yl)methanol is employed as a valuable starting material for the exploration of new chemical reactions and synthetic pathways. Its unique properties and reactivity enable chemists to investigate novel strategies for the synthesis of complex organic molecules and the development of innovative chemical processes.

Upstream product

• 160599-70-2 2,5-dibromo-3-chloropyridine 
• 68-12-2 N,N-dimethyl-formamide 
• 1189513-51-6 5-bromo-3-chloro-pyridine-2-carboxylic acid 
• 1214336-41-0 3-chloro-5-bromo-pyridine-2-carboxylic acid methyl ester 

Relevant articles and documents

CYCLIC COMPOUNDS AND METHODS OF USING SAME

The present application relates to compounds of Formula (I), as defined herein, and pharmaceutically acceptable salts thereof which are MALT1 inhibitors. The present application also describes pharmaceutical composition comprising a compound of Formula (I), and pharmaceutically acceptable salts thereof, and methods of using the compounds and compositions for treating diseases, such as cancer, autoimmune disorders, and inflammatory disorders.

1-(HET)ARYLSULFONYL-(PYRROLIDINE OR PIPERIDINE)-2-CARBOXAMIDE DERIVATIVES AND THEIR USE AS TRPA1 ANTAGONISTS

The invention is concerned with the compounds of formula I and salts thereof and other compounds of formulas II-IX as disclosed herein. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formulas I-IX as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain or asthma.

HETEROARYL SUBSTITUTED HETEROCYCLYL SULFONES

The invention relates to aryl substituted heterocyclyl sulfones as voltage gated calcium channel blockers, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.

BIARYL COMPOUNDS USEFUL FOR THE TREATMENT OF HUMAN DISEASES IN ONCOLOGY, NEUROLOGY AND IMMUNOLOGY

The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.

GPR119 AGONIST

A compound represented by the formula (II) is a GPR119 agonist, and is used as an agent for treating diabetes: wherein each of R23, R24, and R25 is hydrogen, halogen, C1-8 alkyl, C1-8 alkoxy, C1-

GPR119 AGONIST

A cyclic amine derivative represented by the formula (II) is a GPR119 agonist, and is used as an agent for treating diabetes. wherein Ar0 is phenyl or phenyl having a substituent such as C1-8 alkylsulfonyl or the like, pyridyl, or pyridyl having a substituent such as C1-8 alkylsulfonyl; A0 is (CH2)p, O, or the like; B0 is (CH2)q, or the like, provided that B0 is neither O nor NR25 when A0 is O or NR24; one of U0 and V0 is N, and the other is N or CR26; each of X0\ and Y0 is C1-3 alkylene or C1-3 alkylene having a substituent; R23 is a C1-8 alkyl group or the like; each of R21 and R22 is hydrogen, a halogen atom, or the like.