120788-80-9Relevant articles and documents
Total Synthesis of Methynolide
Ditrich, Klaus
, p. 789 - 793 (2007/10/02)
In this paper the synthesis of methynolide (1), the aglycone of methymycin, a 12-membered macrolide antibiotic is described.We have used the chiral C-1 to C-8 segment 10 which has been combined with the C-9 to C-13 segment 9 to form the carbon skeleton of methynolide.Cyclization of the seco-acid 14 has been accomplished by intramolecular esterification.
Stereoselective Synthesis of Alcohols, XXXI. - Stereoselective C-C Bond Formation Using Chiral Z-Pentenylboronates
Hoffmann, Reinhard W.,Ditrich, Klaus,Koester, Gerhard,Stuermer, Rainer
, p. 1783 - 1790 (2007/10/02)
Using 1,2-dicyclohexyl-1,2-ethanediol as chiral auxiliary, the enantiomerically pure Z-pentenylboronate 9c was obtained.Its addition to benzaldehyde proceeded with complete transfer of chirality to give the syn-E-homoallyl alcohol 11.The ability of the re