120912-37-0

Basic information

• Product Name: 5-INDANYL ISOCYANATE
• Synonyms: 1H-Indene,2,3-dihydro-5-isocyanato-(9CI);5-Indanyl isocyanate;5-Isocyanatoindane;5-Indanyl isocyanate ,98%;5-isocyanatoindane(SALTDATA: FREE);511900_ALDRICH;5-isocyanato-2,3-dihydro-1H-indene
• CAS NO: 120912-37-0
• Molecular Formula: C₁₀H₉NO
• Molecular Weight: 159.18
• Product Categories: ISOCYANATE;Isocyanates;Nitrogen Compounds;Organic Building Blocks
• Mol File: 120912-37-0.mol

Chemical Properties

• Boiling Point: 245 °C(lit.)
• Flash Point: 214 °F
• Appearance: /
• Density: 1.106 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0101mmHg at 25°C
• Refractive Index: n20/D 1.56(lit.)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-INDANYL ISOCYANATE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-INDANYL ISOCYANATE(120912-37-0)
• EPA Substance Registry System: 5-INDANYL ISOCYANATE(120912-37-0)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 23-26-36
• RIDADR: UN 2206 6.1/PG 3
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 120912-37-0(Hazardous Substances Data)

Usage

Uses

Used in Polymer Industry:
5-Indanyl Isocyanate is used as a monomer in the production of various polymers for its ability to react with a broad range of compounds, resulting in materials with unique properties.
Used in Pharmaceutical Industry:
5-Indanyl Isocyanate is used as a key intermediate in the synthesis of pharmaceuticals, contributing to the development of new drugs with specific therapeutic properties.
Used in Coatings Industry:
5-Indanyl Isocyanate is used as a component in the formulation of coatings, providing enhanced properties such as durability, adhesion, and resistance to various environmental factors.
Used in Adhesives Industry:
5-Indanyl Isocyanate is used in the production of adhesives, offering improved bonding strength and resistance to different substrates and conditions.
Used in Surface Treatment Industry:
5-Indanyl Isocyanate is employed in surface treatment processes, enhancing the properties of materials such as metals, plastics, and textiles, and providing benefits like corrosion resistance, wear resistance, and improved appearance.

InChI:InChI=1/C10H9NO/c12-7-11-10-5-4-8-2-1-3-9(8)6-10/h4-6H,1-3H2

Upstream product

• 32315-10-9 bis(trichloromethyl) carbonate 
• 24425-40-9 indan-5-amine 

Downstream Products

• 1034494-12-6 4-[1-(2-dimethylaminoethyl)-3-(indan-5-yl)ureidomethyl] benzoic acid benzyl ester 
• 941221-68-7 4-{[(2,3-dihydro-1H-inden-5-yl)aminocarbonyl]amino}benzenesulfonamide 
• 1400979-91-0 1-(benzyloxy)-3-(2,3-dihydro-1H-inden-5-yl)urea 
• 1400980-06-4 1-(benzyloxy)-3,5,6,7-tetrahydroindeno[5,6-d]imidazol-2(1H)-one 

Relevant articles and documents

Benzodiazepine derivatives

Compounds of Formula (I), and salts and prodrugs thereof, wherein R1 represents H, optionally substituted C1-6 alkyl or C3-7 cycloalkyl; R2 is NHR12 or (CH2)s R13 where 5 is 0, 1 or 2; R3 represents C1-6 alkyl, halo or NR6 R7 ; R4 and R5 are H, C1-12 alkyl optionally substituted by NR9 R9' or an azacyclic or azabicyclic group, optionally substituted C4-9 cycloalkyl, C4-9 cycloalkyl C1-4 alkyl, aryl, arylC1-6 alkyl or azacyclic or azabicyclic groups, or R4 and R5 together form the residue of an optionally substituted azacyclic or azabicyclic ring system; x is 0, 1, 2 or 3; R12 is optionally substituted phenyl or pyridyl; R13 represents a group (A) wherein R14 is H or C1-6 alkyl; R15 is H, C1-6 alkyl, halo or NR6 R7 ; and the dotted line is an optional covalent bond; are CCK and/or gastrin antagonists useful in therapy. STR1