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N(2),3-ethenodeoxyguanosine is an etheno-substituted purine nucleoside derivative that exhibits fluorescent and biochemical properties. It is a promutagenic lesion found in normal animal and human tissues, and is believed to play a significant role in the etiology of cancer related to diet and lifestyle.

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  • 121055-53-6 Structure
  • Basic information

    1. Product Name: N(2),3-ethenodeoxyguanosine
    2. Synonyms: N(2),3-ethenodeoxyguanosine;5a,6,7,8-Tetrahydro-1-(2-deoxy-β-D-ribofuranosyl)-1H-imidazo[2,1-b]purin-4(5H)-one;N2,3-Etheno-2'-deoxy Guanosine;1-(2-Deoxy-β-D-erythro-pentofuranosyl)-1H-iMidazo[2,1-b]purin-4(5H)-one
    3. CAS NO:121055-53-6
    4. Molecular Formula: C12H13N5O4
    5. Molecular Weight: 291.26272
    6. EINECS: N/A
    7. Product Categories: Bases & Related Reagents;Carbohydrates & Derivatives;Nucleotides;Carbohydrates & Derivatives, Nucleotides, Bases & Related Reagents
    8. Mol File: 121055-53-6.mol
  • Chemical Properties

    1. Melting Point: >273°C (dec.)
    2. Boiling Point: °Cat760mmHg
    3. Flash Point: °C
    4. Appearance: /
    5. Density: 1.99g/cm3
    6. Refractive Index: 1.915
    7. Storage Temp.: -20°C Freezer
    8. Solubility: DMSO
    9. CAS DataBase Reference: N(2),3-ethenodeoxyguanosine(CAS DataBase Reference)
    10. NIST Chemistry Reference: N(2),3-ethenodeoxyguanosine(121055-53-6)
    11. EPA Substance Registry System: N(2),3-ethenodeoxyguanosine(121055-53-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 121055-53-6(Hazardous Substances Data)

121055-53-6 Usage

Uses

Used in Research Applications:
N(2),3-ethenodeoxyguanosine is used as a research tool for studying the formation and effects of etheno-DNA adducts in various biological processes. Its fluorescent properties allow for the detection and analysis of these adducts, providing valuable insights into the mechanisms of mutagenesis and carcinogenesis.
Used in Pharmaceutical Development:
N(2),3-ethenodeoxyguanosine is used as a potential target for the development of drugs aimed at preventing or reversing the formation of etheno-DNA adducts. By modulating the biochemical pathways involved in their formation, these drugs may help to reduce the risk of cancer associated with diet and lifestyle factors.
Used in Diagnostic Applications:
N(2),3-ethenodeoxyguanosine is used as a biomarker for the detection and monitoring of cancer risk in individuals. Its presence in tissues can indicate exposure to carcinogenic agents and provide a basis for early intervention and prevention strategies.
Used in Environmental Monitoring:
N(2),3-ethenodeoxyguanosine is used as an indicator of environmental exposure to carcinogenic compounds. By measuring its levels in various environmental samples, researchers can assess the potential health risks associated with exposure to these agents and inform public health policies and regulations.

Check Digit Verification of cas no

The CAS Registry Mumber 121055-53-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,1,0,5 and 5 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 121055-53:
(8*1)+(7*2)+(6*1)+(5*0)+(4*5)+(3*5)+(2*5)+(1*3)=76
76 % 10 = 6
So 121055-53-6 is a valid CAS Registry Number.
InChI:InChI=1/C12H13N5O4/c18-4-7-6(19)3-8(21-7)17-5-14-9-10(20)15-12-13-1-2-16(12)11(9)17/h1-2,5-8,18-19H,3-4H2,(H,13,15,20)/t6-,7+,8?/m0/s1

121055-53-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name N2,3-Etheno-2'-deoxy Guanosine

1.2 Other means of identification

Product number -
Other names 1-(2-Deoxy-D-erythro-pentofuranosyl)-1H-imidazo[2,1-b]purin-4(5H) -one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:121055-53-6 SDS

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