1213455-73-2 Usage
Uses
Used in Organic Synthesis:
(R)-2-(o-ethylphenyl)pyrrolidine is utilized as an intermediate in organic synthesis for the creation of various complex molecules and pharmaceutical compounds. Its unique structure and reactivity make it a valuable building block in the development of novel chemical entities.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (R)-2-(o-ethylphenyl)pyrrolidine is employed as a key component in the research and development of new drugs. Its potential pharmacological properties are being explored for the treatment of various medical conditions, making it a promising candidate for future therapeutic applications.
Used in Chiral Compounds:
Due to its chiral center, (R)-2-(o-ethylphenyl)pyrrolidine is also used in the study and development of chiral compounds. Chirality plays a crucial role in the efficacy and safety of pharmaceuticals, and this compound contributes to the understanding and application of chiral chemistry in drug design.
Check Digit Verification of cas no
The CAS Registry Mumber 1213455-73-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,3,4,5 and 5 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1213455-73:
(9*1)+(8*2)+(7*1)+(6*3)+(5*4)+(4*5)+(3*5)+(2*7)+(1*3)=122
122 % 10 = 2
So 1213455-73-2 is a valid CAS Registry Number.
1213455-73-2Relevant articles and documents
Zinc-Catalyzed Asymmetric Hydrosilylation of Cyclic Imines: Synthesis of Chiral 2-Aryl-Substituted Pyrrolidines as Pharmaceutical Building Blocks
W?glarz, Izabela,Michalak, Karol,Mlynarski, Jacek
, p. 1317 - 1321 (2021)
The first successful enantioselective hydrosilylation of cyclic imines promoted by a chiral zinc complex is reported. In situ generated zinc-ProPhenol complex with silane afforded pharmaceutically relevant enantioenriched 2-aryl-substituted pyrrolidines in high yields and with excellent enantioselectivities (up to 99% ee). The synthetic utility of presented methodology is demonstrated in an efficient synthesis of the corresponding chiral cyclic amines, being pharmaceutical drug precursors to the Aticaprant and Larotrectinib. (Figure presented.).
