Suzuki coupling reactions of (E)- and (Z)-chloroenynes with boronic acids: Versatile access to functionalized 1,3-enynes
A stereoselective, palladium-catalyzed, cross-coupling reaction between chloroenynes 4 and boronic acids was successfully developed. This procedure is general and provides de-sired functionalized enynes 1 in high yields. The scope and limitations of this new reaction are described.