- Reaction of 2,5-Bis(trifluoromethyl)-1,3,4-oxadiazole with Primary Amines. Synthesis of 4-Substituted-3,5-bis(trifluoromethyl)-4H-1,2,4-triazoles
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Reaction of 3,5-bis(trifluoromethyl)-1,3,4-oxadiazole (1a) with primary amines under a variety of conditions conveniently produced 4-substituted-3,5-bis(trifluoromethyl)-4H-1,2,4-triazoles 4a in 26-85percent yield.Alkyl amines reacted with 1a in methanol
- Reitz, David B.,Finkes, Michael J.
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p. 225 - 230
(2007/10/02)
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