cas 121639-09-6, N-(2,3-DIMETHOXYPHENYL)ACETAMIDE | Articles data ｜lookchem

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121639-09-6

Articles about 121639-09-6Total 2 be found

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Aerobic oxidative homocoupling reaction of anilides using heterogeneous metal catalysts
We have developed a heterogeneous catalytic oxidative homocoupling reaction of dimethoxyanilides under an oxygen atmosphere. The resulting homo-dimers are useful for the construction of heterocycles, demonstrating the potential of heterogeneous metal catalysts.
Fujimoto, Shigenobu,Matsumoto, Kenji,Iwata, Takayuki,Shindo, Mitsuru
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p. 973 - 976
(2017/02/15)

Acetamidoquinone and acetamidohydroxy derivatives as inhibitors for both dihydroxyacetamido epoxidase and dehydrogenase
A series of monohydroxy and dihydroxyacetanilides, acetamidoquinones and bromoacetamidoquinones have been synthesised and tested as substrates and/or inhibitors of highly purified dihydroxyacetamido epoxidase (DHAE) and dihydroxy acetamido dehydrogenase (DHADH) from Streptomyces LL-C10337. None was found to act as substrates but many selectively inhibit the enzymes. Kinetic analysis has shown that all the compounds act as reversible competitive inhibitors with respect to the substrates 2,5-dihydroxyacetanilide and 2,3-epoxy-1,4-benzoquinone-5-acetanilide. Monohydroxy acetanilides showed weak inhibition to these enzymes compared to the dihydroxy derivatives while the more powerful inhibitors were the benzoquinoneacetanilide and its 5-bromo equivalent.
Whiteley, Chris G.
p. 1221 - 1227
(2007/10/03)

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Chemical Properties

Melting Point: 81-83°C
PSA: 47.56000
LogP: 1.73520

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