121649-62-5

Basic information

• Product Name: Benzoic acid, 3,4-diamino-, 2-methylpropyl ester (9CI)
• Synonyms: Benzoic acid, 3,4-diamino-, 2-methylpropyl ester (9CI)
• CAS NO: 121649-62-5
• Molecular Formula: C₁₁H₁₆N₂O₂
• Molecular Weight: 208.25694
• Product Categories: AMINOACID
• Mol File: 121649-62-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzoic acid, 3,4-diamino-, 2-methylpropyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 3,4-diamino-, 2-methylpropyl ester (9CI)(121649-62-5)
• EPA Substance Registry System: Benzoic acid, 3,4-diamino-, 2-methylpropyl ester (9CI)(121649-62-5)

Safety Data

• Hazardous Substances Data: 121649-62-5(Hazardous Substances Data)

Upstream product

• 1588-83-6 4-amino-3-nitrobenzoic acid 
• 121649-60-3 iso-Butyl 4-amino-3-nitrobenzoate 

Relevant articles and documents

PIPERIDINE DERIVATIVES HAVING CCR3 ANTAGONISM

The invention provides low molecular compounds having activity which inhibits binding of CCR3 ligands to CCR3 on target cells, i.e. CCR3 antagonists. The invention also provides compounds represented by formula (I) below, pharmaceutically acceptable acid adducts thereof, or pharmaceutically acceptable C1-C6 alkyl adducts thereof, as well as pharmaceutical compositions comprising them as effective ingredients, which are useful for treatment or prevention of diseases associated with CCR3, such as asthma and allergic rhinitis.

Studies in Antiparasitic Agents: Part 9 - Synthesis of 5(6)-Alkoxycarbonyl-2-substituted-benzimidazoles as Potential Anthelmintics

Methyl 5(6)-alkoxycarbonylbenzimidazole-2-carbamates (5a-5f) and 5(6)-carboxyl analogue (5g) and its salts (6a-6b) have been synthesized starting from 4-amino-3-nitrobenzoic acid (2), and their structures established by elemental analysis and spectral data.The drugs 5a-5g and 6a-6b have been tested for their anthelmintic activity in rodents infested by Ancylostoma ceylanicum, Syphacia obvelata, Nippostrongylus brasiliensis, Hymenolepis nana, Cysticercus fasciolaris, Litomosoides carinii and Dipetalonema viteae and found to cause 100percent elimination of A. ceylanicum hookworms at an oral dose of 25-250 mg/kg but not so effective against other helminths.