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1217201-17-6

3-[2-(4-CHLOROPHENYLTHIO)PHENYL]-N-(4-DIMETHYLAMINOBUTYL)ACRYLAMIDE, also known as A350619 Hydrochloride, is a chemical compound that acts as an activator of guanylyl cyclase (sGC). It has the ability to activate basal sGC and synergistically activate sGC in the presence of NO, making it a potential therapeutic agent for various applications.

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  • 1217201-17-6 Structure

  • Basic information

    1. Product Name: 3-[2-(4-CHLOROPHENYLTHIO)PHENYL]-N-(4-DIMETHYLAMINOBUTYL)ACRYLAMIDE
    2. Synonyms: A-350619 HYDROCHLORIDE;3-[2-(4-CHLOROPHENYLTHIO)PHENYL]-N-(4-DIMETHYLAMINOBUTYL)ACRYLAMIDE
    3. CAS NO:1217201-17-6
    4. Molecular Formula: C21H25ClN2OS
    5. Molecular Weight: 388.95
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1217201-17-6.mol

  • Chemical Properties

    1. Melting Point: 175.2-176.7 °C
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: white/solid
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: H2O: 23 mg/mL
    9. CAS DataBase Reference: 3-[2-(4-CHLOROPHENYLTHIO)PHENYL]-N-(4-DIMETHYLAMINOBUTYL)ACRYLAMIDE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 3-[2-(4-CHLOROPHENYLTHIO)PHENYL]-N-(4-DIMETHYLAMINOBUTYL)ACRYLAMIDE(1217201-17-6)
    11. EPA Substance Registry System: 3-[2-(4-CHLOROPHENYLTHIO)PHENYL]-N-(4-DIMETHYLAMINOBUTYL)ACRYLAMIDE(1217201-17-6)

  • Safety Data

    1. Hazard Codes: Xn,N
    2. Statements: 22-37/38-41-50/53
    3. Safety Statements: 26-36/37/39-60-61
    4. RIDADR: UN 3077 9/PG 3
    5. WGK Germany: 3
    6. RTECS:
    7. HazardClass: N/A
    8. PackingGroup: N/A
    9. Hazardous Substances Data: 1217201-17-6(Hazardous Substances Data)

1217201-17-6 Usage

Uses

Used in Pharmaceutical Industry:
3-[2-(4-CHLOROPHENYLTHIO)PHENYL]-N-(4-DIMETHYLAMINOBUTYL)ACRYLAMIDE is used as a guanylyl cyclase (sGC) activator for the treatment of erectile dysfunction (ED). As an sGC stimulator, it may be more effective than PDE5 inhibitors in treating ED, offering a novel therapeutic approach for patients with this condition.

Check Digit Verification of cas no

The CAS Registry Mumber 1217201-17-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,7,2,0 and 1 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1217201-17:
(9*1)+(8*2)+(7*1)+(6*7)+(5*2)+(4*0)+(3*1)+(2*1)+(1*7)=96
96 % 10 = 6
So 1217201-17-6 is a valid CAS Registry Number.

1217201-17-6Upstream product

1217201-17-6Downstream Products

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