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ATORVASTATIN-D5 LACTONE is a labeled intermediate of Atorvastatin, a potent inhibitor of MAP kinase and/or HMG-CoA reductase. It is a light yellow solid with significant potential in the treatment of inflammation and other related conditions.

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  • 1217749-86-4 Structure
  • Basic information

    1. Product Name: ATORVASTATIN-D5 LACTONE
    2. Synonyms: ATORVASTATIN-D5 LACTONE;5-(4-Fluorophenyl)-2-(1-methylethyl)-N-phenyl-(4-phenyl-d5)-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide;Atorvastatin-d5 d-Lactone
    3. CAS NO:1217749-86-4
    4. Molecular Formula: C33H28D5FN2O4
    5. Molecular Weight: 545.66
    6. EINECS: N/A
    7. Product Categories: All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Isotope Labeled Compounds;Metabolites & Impurities;Pharmaceuticals;Isotope Labelled Compounds
    8. Mol File: 1217749-86-4.mol
  • Chemical Properties

    1. Melting Point: 98-100°C
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: -20°C Freezer, Under Inert Atmosphere
    8. Solubility: Methanol (Slightly), Ethyl Acetate (Slightly)
    9. CAS DataBase Reference: ATORVASTATIN-D5 LACTONE(CAS DataBase Reference)
    10. NIST Chemistry Reference: ATORVASTATIN-D5 LACTONE(1217749-86-4)
    11. EPA Substance Registry System: ATORVASTATIN-D5 LACTONE(1217749-86-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1217749-86-4(Hazardous Substances Data)

1217749-86-4 Usage

Uses

Used in Pharmaceutical Industry:
ATORVASTATIN-D5 LACTONE is used as an intermediate in the synthesis of Atorvastatin for the treatment of inflammation. It serves as an inhibitor of MAP kinase and/or HMG-CoA reductase, playing a crucial role in managing inflammatory conditions and potentially contributing to the development of novel therapeutic agents.
Additionally, due to its inhibitory properties, ATORVASTATIN-D5 LACTONE may also be utilized in research and development for exploring its potential applications in other areas of medicine, such as cardiovascular health, where the inhibition of HMG-CoA reductase can be beneficial.

Check Digit Verification of cas no

The CAS Registry Mumber 1217749-86-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,7,7,4 and 9 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1217749-86:
(9*1)+(8*2)+(7*1)+(6*7)+(5*7)+(4*4)+(3*9)+(2*8)+(1*6)=174
174 % 10 = 4
So 1217749-86-4 is a valid CAS Registry Number.

1217749-86-4Upstream product

1217749-86-4Downstream Products

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