Pd-catalyzed decarboxylative arylation of thiazole benzoxazole, and polyfluorobenzene with substituted benzoic acids
(Figure Represented) A Pd-catalyzed decarboxylative coupling of thiazoles and benzoxazole with various substituted benzoic acids Is developed. The reaction is compatible with both electron-rich and electron-poor benzoic acids. It can also be extended to the synthesis of polyfluoro-substituted biaryls using polyfluorobenzenes as the starting materials.