- NEW IMIDAZOLONE DERIVATIVES, PREPARATION THEREOF AS DRUGS, PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF AS PROTEIN KINASE INHIBITORS, IN PARTICULAR CDC7
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The present invention relates to imidazolone derivatives of formula (I) to methods of preparing such derivatives, intermediates thereto, pharmaceutical compositions comprising such derivatives, and methods of inhibiting protein kinase, and methods of treatment comprising administration of such derivatives.
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Page/Page column 60
(2009/10/17)
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- 2-AMINO-SUBSTITUTED DERIVATIVES OF BENZIMIDAZOLES FROM 2-ISOTHIOCYANATO CARBOXYLATES
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2-isothiocyanato carboxylates react with o-phenylenediamine to give N,N'-substituted thioureas, which cyclize to yield 2-amino-substituted derivatives of imidazole.The structure of these compounds was corroborated by IR, UV, 1H, 13C NMR, and mass spectral
- Floch, Lubomir,Uher, Michal,Lesko, Jan
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p. 206 - 214
(2007/10/02)
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