1219818-13-9Relevant articles and documents
OLIGOOXOPIPERAZINES AND METHODS OF MAKING AND USING THEM
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, (2012/03/08)
The present invention relates to oligooxopiperazines and their use. Methods for preparing oligooxopiperazines are also disclosed.
Oligooxopiperazines as nonpeptidic α-helix mimetics
Tosovska, Petra,Arora, Paramjit S.
supporting information; experimental part, p. 1588 - 1591 (2010/06/16)
Chemical Reaction Repretatio A new class of nonpeptidic α-helix mlmetics derived from a-amino acids and featuring chlral backbones is described. NMR and circular dichroism spectroscopies, in combination with molecular modeling studies, provide compelling evidence that ollgooxopiperazlne dimers adopt stable conformations that reproduce the arrangement of i, i+4, and i+7 residues on an α-helix.