1221446-33-8 Usage
Uses
Used in Pharmaceutical Synthesis:
2-Benzylthiophenylboronic acid is used as a key intermediate in the synthesis of pharmaceutical compounds, contributing to the development of new medicines. Its reactivity and ability to form stable bonds with other atoms make it a crucial component in the construction of complex molecular structures.
Used in Organic Synthesis:
In the field of organic chemistry, 2-benzylthiophenylboronic acid is employed as a versatile building block for the synthesis of various organic compounds. Its unique structure and properties allow for the creation of a wide range of molecules with potential applications in different industries.
Used in Medicinal Chemistry Research:
2-Benzylthiophenylboronic acid is utilized as a component in medicinal chemistry research, where it aids scholars in studying molecule transformations and interactions. This understanding is essential for the discovery and development of novel therapeutic agents and pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 1221446-33-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,1,4,4 and 6 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1221446-33:
(9*1)+(8*2)+(7*2)+(6*1)+(5*4)+(4*4)+(3*6)+(2*3)+(1*3)=108
108 % 10 = 8
So 1221446-33-8 is a valid CAS Registry Number.
1221446-33-8Relevant articles and documents
Halogen-lithium exchange versus deprotonation: regioselective mono- and dilithiation of aryl benzyl sulfides. A simple approach to α,2-dilithiotoluene equivalents
Kli?, Tomasz,Serwatowski, Janusz,Wesela-Bauman, Grzegorz,Zadrozna, Magdalena
experimental part, p. 1685 - 1689 (2010/06/13)
Halogen-lithium exchange and deprotonation reactions between aryl benzyl sulfides and alkyllithiums were investigated. The resultant mono- and dilithiated intermediates were converted into the corresponding aldehydes and boronic, or carboxylic acids in good yields. It was found that diethyl ether stabilizes the ortho-lithiated compounds toward isomerisation to the benzylic derivatives. The process occurs easily in THF at low temperature and is a facile route to the α,2-dilithiotoluene derivative which can be transformed into a dicarboxylic acid on treatment with CO2.
