- METHODS AND INTERMEDIATES FOR PREPARING DEUTETRABENAZINE
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Disclosed is a process for the preparation of deutetrabenazine and intermediates useful in the preparation thereof. Disclosed are also process for making amorphous deutetrabenazine.
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Page/Page column 32; 33; 36; 37; 39; 40; 42
(2019/07/17)
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- A NOVEL PROCESS FOR PREPARATION OF DEUTETRABENAZINE
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A novel process for preparation of Deutetrabenazine ((RR, SS)-l,3,4,6,7-llb-Hexahydro-9,10-di(methoxy-d6)-3-(2-methylpropyl)-2H- benzo [a] quinolizin-2-one) of formula I comprises of methylation of N-(2-(3,4-dihydroxy-phenyl)-ethyl)-formamide c
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Page/Page column 20-21
(2019/08/26)
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- BENZOQUINOLINE INHIBITORS OF VESICULAR MONOAMINE TRANSPORTER 2
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The present invention relates to new benzoquinoline inhibitors of vesicular monoamine transporter 2 (VMAT2), pharmaceutical compositions thereof, and methods of use thereof.
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- ANALOGS OF DEUTETRABENAZINE, THEIR PREPARATION AND USE
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The disclosure is directed to deutetrabenazine analogs, compositions comprising same and methods of detecting same in compositions comprising deutetrabenazine.
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- NOVEL PROCESS FOR PREPARATION OF TETRABENAZINE AND DEUTETRABENAZINE
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The present invention provides process for preparation of dihydroxy benzoquinoline compound (III) comprising reacting dihydroxy isoquinoline compound (IV) or a salt thereof with (2-acetyl-4-methyl-pentyl)-trimethyl-ammonium iodide (V) and further 5 converting it to tetrabenazine (I) and deutetrabenazine (II).
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Page/Page column 10
(2017/11/15)
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- BENZOQUINOLINE INHIBITORS OF VESICULAR MONOAMINE TRANSPORTER 2
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The present invention relates to new benzoquinoline inhibitors of vesicular monoamine transporter 2 (VMAT2), pharmaceutical compositions thereof, and methods of use thereof. (Formula (I))
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- BENZOQUINOLINE INHIBITORS OF VESICULAR MONOAMINE TRANSPORTER 2
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The present invention relates to new benzoquinoline inhibitors of vesicular monoamine transporter 2 (VMAT2), pharmaceutical compositions thereof, and methods of use thereof. (I)
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- METHODS OF TREATING ABNORMAL MUSCULAR ACTIVITY
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Methods for treating abnormal muscular activity are disclosed. The methods may be performed remotely and permit monitoring of a subject outside a healthcare provider's office.
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- BENZOQUINOLONE INHIBITORS OF VMAT2
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The present invention relates to new benzoquinolone inhibitors of VMAT2, pharmaceutical compositions thereof, and methods of use thereof. Formula (I)
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- BENZOQUINOLINE INHIBITORS OF VESICULAR MONOAMINE TRANSPORTER 2
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The present invention relates to new benzoquinoline inhibitors of vesicular monoamine transporter 2 (VMAT2), pharmaceutical compositions thereof, and methods of use thereof.
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Page/Page column 31-32
(2010/04/30)
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