A series of renin inhibitors containing lactam-bridged P1-P1' dipeptide mimetics based on the ACHPA (4(S)-amino-5-cyclohexyl-3(S)-hydroxypentanoic acid) design was studied.The inhibitors were obtained by aldol addition of various lac
Williams, Peter D.,Perlow, Debra S.,Payne, Linda S.,Holloway, M. Katharine,Siegl, Peter K. S.,et al.
p. 887 - 900
(2007/10/02)
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