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2-(5-Aminopyridin-2-yl)-2-methylpropanenitrile is a chemical compound with the molecular formula C10H12N4. It is a derivative of 2-amino-5-picoline and is characterized by its yellow solid appearance and a molecular weight of 184.23 g/mol. 2-(5-Aminopyridin-2-yl)-2-methylpropanenitrile is known for its chemical reactivity and potential biological activity, which makes it a valuable component in the synthesis of pharmaceuticals and agrochemicals. Its potential medicinal properties are currently under research for applications in drug discovery and development.

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  • 1226776-95-9 Structure
  • Basic information

    1. Product Name: 2-(5-Aminopyridin-2-yl)-2-methylpropanenitrile
    2. Synonyms: 2-(5-Aminopyridin-2-yl)-2-methylpropanenitrile;2-(5-AMinopyridin-2-yl)-2-Methylpropanenitrille;2-(5-AMino-2-pyridyl)-2-Methylpropanenitrile;2-(5-Amino-pyridin-2-yl)-2-methyl-propionitrile;5-amino-α,α-dimethyl-2-Pyridineacetonitrile;2-(5-Aminopyridin-2-yl)
    3. CAS NO:1226776-95-9
    4. Molecular Formula: C9H11N3
    5. Molecular Weight: 161.20374
    6. EINECS: N/A
    7. Product Categories: OLED materials,pharm chemical,electronic
    8. Mol File: 1226776-95-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 345.922 °C at 760 mmHg
    3. Flash Point: 163.008 °C
    4. Appearance: /
    5. Density: 1.111
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-(5-Aminopyridin-2-yl)-2-methylpropanenitrile(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-(5-Aminopyridin-2-yl)-2-methylpropanenitrile(1226776-95-9)
    11. EPA Substance Registry System: 2-(5-Aminopyridin-2-yl)-2-methylpropanenitrile(1226776-95-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1226776-95-9(Hazardous Substances Data)

1226776-95-9 Usage

Uses

Used in Pharmaceutical Industry:
2-(5-Aminopyridin-2-yl)-2-methylpropanenitrile is used as an intermediate in the synthesis of various pharmaceuticals for its potential medicinal properties. It contributes to the development of new therapeutic agents due to its chemical structure and reactivity.
Used in Agrochemical Industry:
In the agrochemical sector, 2-(5-Aminopyridin-2-yl)-2-methylpropanenitrile is utilized as a building block in the creation of pesticides. Its role in this industry is to provide a foundation for the development of effective and novel agrochemicals.
Used in Research and Development:
2-(5-Aminopyridin-2-yl)-2-methylpropanenitrile is used as a research compound in laboratory settings. Its chemical reactivity and potential biological activity make it a valuable tool for scientists working on drug discovery and development, as well as for exploring its possible applications in medicine and agriculture.

Check Digit Verification of cas no

The CAS Registry Mumber 1226776-95-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,6,7,7 and 6 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1226776-95:
(9*1)+(8*2)+(7*2)+(6*6)+(5*7)+(4*7)+(3*6)+(2*9)+(1*5)=179
179 % 10 = 9
So 1226776-95-9 is a valid CAS Registry Number.

1226776-95-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(5-Amino-2-pyridyl)-2-methylpropanenitrile

1.2 Other means of identification

Product number -
Other names 2-(5-Aminopyridin-2-yl)-2-methylpropanenitrile

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1226776-95-9 SDS

1226776-95-9Downstream Products

1226776-95-9Relevant articles and documents

PROCESS FOR THE PREPARATION OF SUBSTITUTED IMIDAZO[4,5-C]QUINOLINE COMPOUNDS, INTERMEDIATES AND POLYMORPHS THEREOF

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Page/Page column 36, (2015/12/08)

The present invention relates to a process for preparation of substituted imidazo[4,5- c]quinoline compounds (the compounds of formula I as described) and intermediates thereof. The present invention also relates to polymorphs of a compound encompassed in the compound of formula I and their use in the treatment of proliferative disorders, particularly cancers.

FUSED HETEROARYLS AND THEIR USES

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Paragraph 0146; 0150, (2013/07/31)

Provided are certain fused heteroaryls, compositions thereof and methods of use therefor.

FUSED HETEROARYLS AND THEIR USES

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Page/Page column 31, (2012/04/04)

Provided are certain fused heteroaryls, compositions thereof and methods of use therefor.

SUBSTITUTED IMIDAZOQUINOLINE DERIVATIVES AS KINASE INHIBITORS

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Page/Page column 51, (2012/02/02)

The present invention relates to substituted imidazo[4,5-c]quinoline derivatives, the compounds of formula (I), wherein R1 R2, R3, R4, R5, R6 and R7 are as defined in the specification, processes for their preparation, pharmaceutical compositions comprising compounds of formula (I), and their use in the treatment of diseases or disorders mediated by one or more kinases, particularly proliferative diseases or disorders such as cancer. These compounds can also be used in the treatment of inflammatory diseases and angiogenesis related disorders.

SUBSTITUTED IMIDAZOQUINOLINE DERIVATIVES

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Page/Page column 43, (2012/06/30)

The present invention relates to substituted imidazo[4,5-c]quinoline derivatives of formula (I), wherein R1, R2 and R3 are as defined in the specification, processes for their preparation, pharmaceutical compositions comprising compounds of the present invention and their use in the treatment of diseases or disorders mediated by one or more kinases, particularly proliferative diseases or disorders such as cancer. These compounds can also be used in the treatment of inflammation and angiogenesis related disorders.

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