The present application describes compounds of Formula I and Formula IA and as disclosed herein, that are useful as anti-microbial agents, including as antibacterial, disinfectant, antifungal, germicidal or antiviral agents.
-
Page/Page column 109-110
(2012/05/05)
Structure stability/activity relationships of sulfone stabilized N,N-dichloroamines
Structure stability/activity relationships (SXR) of a new class of N,N-dichloroamine compounds were explored to improve antimicrobial activity against Escherichia coli, Staphylococcus aureus, and Candida albicans while maintaining aqueous solution stability. This study identified a new class of solution-stable and topical antimicrobial agents. These agents are sulfone-stabilized and possess either a quaternary ammonium or sulfonate appendages as a water solubilizing group. Several unique challenges were confronted in the synthesis of these novel compounds which are highlighted in the discussion.
Low, Eddy,Kim, Bum,Francavilla, Charles,Shiau, Timothy P.,Turtle, Eric D.,O'Mahony, Donogh J.R.,Alvarez, Nichole,Houchin, Ashley,Xu, Ping,Zuck, Meghan,Celeri, Chris,Anderson, Mark B.,Najafi, Ramin,Jain, Rakesh K.
p. 3682 - 3685
(2011/08/06)
More Articles about upstream products of 1226913-81-0