1227700-45-9 Usage
Uses
Used in Pharmaceutical Industry:
6-Methoxypyridine-2-boronic acid MIDA ester is used as a reagent for coupling reactions in the pharmaceutical industry. It is particularly valuable for its role in Suzuki Cross-Coupling reactions, which are essential for the synthesis of complex organic compounds, including those with potential pharmaceutical applications. The use of this MIDA ester allows for more stable and efficient cross-couplings, leading to improved yields and better overall results in the synthesis of target molecules.
Used in Chemical Research:
In the field of chemical research, 6-Methoxypyridine-2-boronic acid MIDA ester is used as a reagent for coupling reactions, particularly in the context of Suzuki Cross-Coupling. This ester provides a stable and reliable alternative to traditional boronic acids, enabling researchers to overcome challenges associated with cross-coupling reactions. Its use in research settings allows for the exploration of new synthetic pathways and the development of novel compounds with potential applications in various industries, including pharmaceuticals, materials science, and agrochemicals.
Used in Material Science:
6-Methoxypyridine-2-boronic acid MIDA ester is also used in the field of material science as a reagent for coupling reactions. Its application in Suzuki Cross-Coupling reactions enables the synthesis of complex organic compounds that can be used to create advanced materials with unique properties. These materials can be utilized in various applications, such as in the development of new electronic devices, sensors, and energy storage systems.
Check Digit Verification of cas no
The CAS Registry Mumber 1227700-45-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,7,7,0 and 0 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1227700-45:
(9*1)+(8*2)+(7*2)+(6*7)+(5*7)+(4*0)+(3*0)+(2*4)+(1*5)=129
129 % 10 = 9
So 1227700-45-9 is a valid CAS Registry Number.
1227700-45-9Relevant articles and documents
Methods for Forming Protected Organoboronic Acids
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Page/Page column 11; 12, (2011/09/14)
Described are methods of forming protected boronic acids that provide in a manner that is straightforward, scalable, and cost-effective a wide variety of building blocks, such as building blocks containing complex and/or pharmaceutically important structures, and/or provide simple or complex protected organoboronic acid building blocks. A first method includes reacting an imino-di-carboxylic acid and an organoboronate salt. A second method includes reacting a N-substituted morpholine dione and an organoboronic acid.
General method for synthesis of 2-heterocyclic N-methyliminodiacetic acid boronates
Dick, Graham R.,Knapp, David M.,Gillis, Eric P.,Burke, Martin D.
supporting information; experimental part, p. 2314 - 2317 (2010/08/04)
A wide range of 2-pyridyl and other difficult-to-access heterocyclic N-methyliminodiacetic acid boronates can be readily prepared from the corresponding bromides via a new method involving direct transligation of 2-heterocyclic trialkoxyborate salts with N-methyliminodiacetic acid (MIDA) at elevated temperatures.
