- TEAD INHIBITORS AND USES THEREOF
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The present invention provides compounds, compositions thereof, and methods of using the same.
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Paragraph 00465; 00718; 00719
(2020/12/11)
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- CRYSTALLINE FORMS OF A 3-[2-METHANESULFONYL-1-(4-TRIFLUOROMETHYL-PHENOXY)ETHYL]PYRROLIDINE COMPOUND
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The invention provides crystalline hydrochloride salts of (S)-3-[(S)-2-methanesulfonyl-1-(4-trifluoromethylphenoxy)ethyl]pyrrolidine. This invention also provides pharmaceutical compositions comprising the crystalline salts, processes and intermediates for preparing the crystalline salts, and methods of using the crystalline salts to treat diseases.
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Page/Page column 35; 36
(2013/04/13)
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- SEROTONIN REUPTAKE INHIBITORS
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In one aspect, the invention relates to compounds of formula I: where X, Y, R1, R2, R3, R4, R4, and n are as defined in the specification, or a pharmaceutically acceptable salt thereof. The compounds of formula I are serotonin reuptake inhibitors. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.
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Page/Page column 21-22
(2012/04/18)
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- SEROTONIN REUPTAKE INHIBITORS
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In one aspect, the invention relates to compounds of formula (I) where Y, R1, R2, n, and Q are as defined in the specification, or a pharmaceutically acceptable salt thereof. The compounds of formula I are serotonin reuptake inhibito
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Page/Page column 48-49
(2012/06/16)
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- ARYLVINYLAZACYCLOALKANE COMPOUNDS FOR CONSTIPATION
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The present invention relates to methods of treating constipation and enhancing colonic motility by administration of 5-((E)-2 pyrrolidin-3-ylvinyl)pyrimidine or a pharmaceutically acceptable salt thereof.
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- 3-PHENOXYMETHYLPYRROLIDINE COMPOUNDS
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In one aspect, the invention relates to compounds of formula I: where R1-6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. The compounds of formula I are serotonin and norepinephrine reuptake inhibitors. In a
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Page/Page column 19
(2011/02/18)
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- NOVEL COMPOUNDS
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The present invention relates to compounds that bind to and modulate the activity of neuronal nicotinic acetylcholine receptors, to novel salts thereof, to processes for preparing these compounds, novel chemical compounds useful as intermediates, pharmaceutical compositions containing the product compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders, including those associated with dysfunction of the central nervous system (CNS).
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Page/Page column 37
(2010/06/20)
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- SYNTHESIS AND NOVEL SALT FORMS OF (R)-5-((E)-2-(PYRROLIDIN-3-YLVINYL)PYRIMIDINE
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The present invention relates to the stereospecific synthesis of (R)-5-((E)-2-pyrrolidin-3-ylvinyl)pyrimidine, its salt forms, and novel polymorphic forms of these salts.
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Page/Page column 40
(2010/06/20)
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