1228765-06-7 Usage
Uses
Used in Pharmaceutical Industry:
1-Boc-3-fluoropyrrolidine is used as an intermediate in the synthesis of various pharmaceuticals for its ability to protect amines and facilitate the introduction of fluorine-containing functional groups. The fluorine substitution can improve the drug's metabolic stability, lipophilicity, and overall pharmacological profile, leading to enhanced therapeutic efficacy.
Used in Agrochemical Industry:
1-Boc-3-fluoropyrrolidine is employed as a key intermediate in the preparation of agrochemicals, such as pesticides and herbicides. The introduction of fluorine atoms can enhance the bioactivity, selectivity, and environmental persistence of these compounds, making them more effective in controlling pests and weeds.
Used in Organic Synthesis:
As a versatile building block, 1-Boc-3-fluoropyrrolidine is utilized in the synthesis of a wide range of organic compounds, including complex natural products, pharmaceuticals, and specialty chemicals. The Boc protecting group allows for selective amine protection, enabling the synthesis of amines with multiple functional groups.
Used in Material Science:
1-Boc-3-fluoropyrrolidine can be incorporated into the design and synthesis of novel materials with unique properties, such as fluorine-containing polymers, which exhibit improved thermal stability, chemical resistance, and other desirable characteristics for various applications in material science.
Check Digit Verification of cas no
The CAS Registry Mumber 1228765-06-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,8,7,6 and 5 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1228765-06:
(9*1)+(8*2)+(7*2)+(6*8)+(5*7)+(4*6)+(3*5)+(2*0)+(1*6)=167
167 % 10 = 7
So 1228765-06-7 is a valid CAS Registry Number.
1228765-06-7Relevant articles and documents
Synthesis of aminomethylated 4-fluoropiperidines and 3-fluoropyrrolidines
Verniest, Guido,Piron, Karel,Van Hende, Eva,Thuring, Jan Willem,MacDonald, Gregor,Deroose, Frederik,De Kimpe, Norbert
, p. 2509 - 2512 (2010)
A short and efficient synthesis of 4-aminomethyl-4-fluoropiperidines and 3-aminomethyl-3-fluoropyrrolidines is described. These fluorinated azaheterocycles are of specific interest as bifunctional building blocks for fluorinated pharmaceutical compounds.
