Synthesis and Cardiotonic Activity of Novel Biimidazoles
A series of substituted 2,2-bi-1H-imidazoles and related analogues was synthesized and evaluated for inotropic activity.Structure-activity relationship studies based on a nonclassical bioisosteric approach indicated the necessity of a cyano group on one o
Matthews, Donald P.,McCarthy, James R.,Whitten, Jeffrey P.,Kastner, Philip R.,Barney, Charlotte L.,et al.
p. 317 - 327
(2007/10/02)
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