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TERT-BUTYL 2 METHOXY-4-NITROBENZOATE is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1232688-45-7 Structure
  • Basic information

    1. Product Name: TERT-BUTYL 2 METHOXY-4-NITROBENZOATE
    2. Synonyms: TERT-BUTYL 2 METHOXY-4-NITROBENZOATE
    3. CAS NO:1232688-45-7
    4. Molecular Formula: C12H15NO5
    5. Molecular Weight: 253.2512
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1232688-45-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: TERT-BUTYL 2 METHOXY-4-NITROBENZOATE(CAS DataBase Reference)
    10. NIST Chemistry Reference: TERT-BUTYL 2 METHOXY-4-NITROBENZOATE(1232688-45-7)
    11. EPA Substance Registry System: TERT-BUTYL 2 METHOXY-4-NITROBENZOATE(1232688-45-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1232688-45-7(Hazardous Substances Data)

1232688-45-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1232688-45-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,3,2,6,8 and 8 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1232688-45:
(9*1)+(8*2)+(7*3)+(6*2)+(5*6)+(4*8)+(3*8)+(2*4)+(1*5)=157
157 % 10 = 7
So 1232688-45-7 is a valid CAS Registry Number.

1232688-45-7Relevant articles and documents

Design and synthesis of a potent, highly selective, orally bioavailable, retinoic acid receptor alpha agonist

Clarke, Earl,Jarvis, Christopher I.,Goncalves, Maria B.,Kalindjian, S. Barret,Adams, David R.,Brown, Jane T.,Shiers, Jason J.,Taddei, David M.A.,Ravier, Elodie,Barlow, Stephanie,Miller, Iain,Smith, Vanessa,Borthwick, Alan D.,Corcoran, Jonathan P.T.

, p. 798 - 814 (2018/01/01)

A ligand-based virtual screening exercise examining likely bioactive conformations of AM 580 (2) and AGN 193836 (3) was used to identify the novel, less lipophilic RARα agonist 4-(3,5-dichloro-4-ethoxybenzamido)benzoic acid 5, which has good selectivity over the RARβ and RARγ receptors. Analysis of the medicinal chemistry parameters of the 3,5-substituents of derivatives of template 5 enabled us to design a class of drug-like molecules with lower intrinsic clearance and higher oral bioavailability which led to the novel RARα agonist 4-(3-chloro-4-ethoxy-5-isopropoxybenzamido)-2-methylbenzoic acid 56 that has high RARα potency and excellent selectivity versus RARβ (2 orders of magnitude) and RARγ (4 orders of magnitude) at both the human and mouse RAR receptors with improved drug-like properties. This RARα specific agonist 56 has high oral bioavailability (>80%) in both mice and dogs with a good PK profile and was shown to be inactive in cytotoxicity and genotoxicity screens.

Therapeutic Aryl-Amido-Aryl Compounds and Their Use

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Page/Page column 67, (2012/06/18)

The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain aryl-amido-aryl compounds of the following formula (for convenience, collectively referred to herein as “AAA compounds”), which, inter alia, a

THERAPEUTIC ARYL-AM I DO-ARYL COMPOUNDS AND THEIR USE

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Page/Page column 119, (2011/04/14)

The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain aryl-amido-aryl compounds of the following formula (for convenience, collectively referred to herein as "AAA compounds"), which, inter alia, a

DIHYDROPYRIDONE UREAS AS P2X7 MODULATORS

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Page/Page column 57, (2010/07/04)

Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, n, R1, R2, R3, R4 and R5 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of diseases associated with the P2X7 purinergic receptor.

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