Optimization of a novel kinase inhibitor scaffold for the dual inhibition of JAK2 and FAK kinases
The elaboration of a novel scaffold for the inhibition of JAK2 and FAK kinases was targeted in order to provide a dual inhibitor that could target divergent pathways for tumor cell progression.
Zificsak, Craig A.,Gingrich, Diane E.,Breslin, Henry J.,Dunn, Derek D.,Milkiewicz, Karen L.,Theroff, Jay P.,Thieu, Tho V.,Underiner, Ted L.,Weinberg, Linda R.,Aimone, Lisa D.,Albom, Mark S.,Mason, Jennifer L.,Saville, Lisa,Husten, Jean,Angeles, Thelma S.,Finn, James P.,Jan, Mahfuza,O'Kane, Teresa M.,Dobrzanski, Pawel,Dorsey, Bruce D.
p. 133 - 137
(2012/02/15)
More Articles about upstream products of 1232786-26-3