Rhodium(III)-Catalyzed C-H Functionalization of 1-(2H)-Phthalazinones at C8
The rhodium(III) catalyst tris(acetonitrile)pentamethylcyclopentadienylrhodium(III) hexafluoroantimonate ([Cp*Rh(MeCN)3](SbF6)2) reacts with 1-(2H)-phthalazinones to promote a C-H functionalization event at C8. Preparation
ARYL SULFONAMIDES AS SMALL MOLECULE STAT3 INHIBITORS
The present disclosure provides pharmaceutical compositions comprising aryl sulfonamide Stat3 small molecule inhibitors and certain pharmaceutically acceptable salts thereof, and methods of their use for treating cancer.
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Paragraph 00253; 00255; 00270; 00272
(2021/01/29)
ANTIVIRAL COMPOUNDS
The present invention discloses compounds of Formula I wherein the variables in Formula I are defined as described herein. Also disclosed are pharmaceutical compositions containing such compounds and methods for using the compounds of Formula I in the pre
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Page/Page column 48
(2014/09/29)
Synthesis of phthalazinones via palladium(ii)-catalysed intramolecular oxidative C-H/C-H cross-coupling of N′-methylenebenzohydrazides
A palladium(ii)-catalysed intramolecular oxidative C-H/C-H cross-coupling of N′-methylenebenzohydrazides to phthalazin-1(2H)-ones has been developed. This cyclization is believed to mechanistically proceed via electrophilic ortho-palladation and subsequen
Matsuda, Takanori,Tomaru, Yuki,Matsuda, Yoshiya
supporting information
p. 2084 - 2087
(2013/04/23)
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