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(R)-1-(1H-Benzimidazol-2-yl)ethylamine Hydrochloride is a chemical compound characterized by a benzimidazole ring system attached to an ethylamine side chain. As a hydrochloride salt form of the amine, it represents a derivative of benzimidazole. (R)-1-(1H-Benzimidazol-2-yl)ethylamine Hydrochloride is recognized for its potential pharmacological properties, making it a candidate for the development of pharmaceutical drugs. The benzimidazole framework has been extensively studied for its antimicrobial, antiparasitic, and antitumor activities, with the hydrochloride salt form potentially offering enhanced stability and water solubility over the free amine form, thus serving as a valuable tool in pharmacological research and drug development.

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  • 1234996-74-7 Structure
  • Basic information

    1. Product Name: (R)-1-(1H-Benzimidazol-2-yl)ethylamine Hydrochloride
    2. Synonyms: (R)-1-(1H-Benzimidazol-2-yl)ethylamine Hydrochloride;(alphaR)-alpha-Methyl-1H-benzimidazole-2-methanamine hydrochloride;(R)-1-(1H-BENZIMIDAZOL-2-YL)ETHYLAMINE HCL
    3. CAS NO:1234996-74-7
    4. Molecular Formula: C9H12ClN3
    5. Molecular Weight: 197.66468
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1234996-74-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
    8. Solubility: N/A
    9. CAS DataBase Reference: (R)-1-(1H-Benzimidazol-2-yl)ethylamine Hydrochloride(CAS DataBase Reference)
    10. NIST Chemistry Reference: (R)-1-(1H-Benzimidazol-2-yl)ethylamine Hydrochloride(1234996-74-7)
    11. EPA Substance Registry System: (R)-1-(1H-Benzimidazol-2-yl)ethylamine Hydrochloride(1234996-74-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1234996-74-7(Hazardous Substances Data)

1234996-74-7 Usage

Uses

Used in Pharmaceutical Development:
(R)-1-(1H-Benzimidazol-2-yl)ethylamine Hydrochloride is utilized as a key intermediate in the synthesis of various pharmaceutical drugs due to its potential pharmacological properties. (R)-1-(1H-Benzimidazol-2-yl)ethylamine Hydrochloride's structural features allow it to be a versatile building block for the creation of new therapeutic agents.
Used in Antimicrobial Agents:
In the field of antimicrobials, (R)-1-(1H-Benzimidazol-2-yl)ethylamine Hydrochloride is used as a precursor for developing new antibiotics, leveraging the antimicrobial activity often associated with benzimidazole derivatives. Its ability to target and disrupt bacterial processes makes it a promising candidate for combating resistant strains of bacteria.
Used in Antiparasitic Medications:
(R)-1-(1H-Benzimidazol-2-yl)ethylamine Hydrochloride is employed as a component in antiparasitic medications, capitalizing on the antiparasitic effects of benzimidazole compounds. It may be used to treat infections caused by various parasites by interfering with their vital cellular processes.
Used in Antitumor Therapies:
In oncology, (R)-1-(1H-Benzimidazol-2-yl)ethylamine Hydrochloride is used as a starting material for the design of antitumor agents. Its potential to exhibit antitumor activity makes it a candidate for further research into treatments for various types of cancer.
Used in Research Compounds:
Within the research community, (R)-1-(1H-Benzimidazol-2-yl)ethylamine Hydrochloride serves as a research compound for studying the effects of benzimidazole derivatives on biological systems. It aids scientists in understanding the mechanisms of action and potential applications in medicine.
Used in Drug Delivery Systems:
(R)-1-(1H-Benzimidazol-2-yl)ethylamine Hydrochloride may also be used in the development of drug delivery systems to improve the bioavailability and targeting of therapeutic agents, particularly for those derived from benzimidazole chemistry, enhancing their efficacy and reducing side effects.

Check Digit Verification of cas no

The CAS Registry Mumber 1234996-74-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,3,4,9,9 and 6 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1234996-74:
(9*1)+(8*2)+(7*3)+(6*4)+(5*9)+(4*9)+(3*6)+(2*7)+(1*4)=187
187 % 10 = 7
So 1234996-74-7 is a valid CAS Registry Number.

1234996-74-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name (R)-1-(1H-Benzimidazol-2-yl)ethylamine Hydrochloride

1.2 Other means of identification

Product number -
Other names (1R)-1-(1H-Benzimidazol-2-yl)ethanamine hydrochloride (1:1)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1234996-74-7 SDS

1234996-74-7Downstream Products

1234996-74-7Relevant articles and documents

BENZIMIDAZOLE COMPOUNDS THAT ARE VITRONECTIN RECEPTOR ANTAGONISTS

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Page/Page column 30-31, (2008/06/13)

The present invention provides compounds having formula (I) wherein n, p, q and r are each independently selected from 0 or 1; a, b, c, and d each independently represents a carbon or nitrogen atom, with the proviso that no more than two of a, b, c, and d are nitrogen atoms; Y and Y' each independently represents 1-4 optional substituents selected from alkyl, alkoxy, halo, -CF3, and -C(O)OH; R, R, R and R are H or specified substituents; R, R, R, R, R, R, R and R are independently selected from H or C1-C3 alkyl; or a biolabile ester thereof, or a pharmaceutically acceptable salt thereof. Also provided are methods of using these compounds for treating vitronectin-mediated disorders, e.g., cancer, retinopathy, artherosclerosis, vascular restenosis, and osteoporosis.

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