Novel N-[4-(aminosubstituted)phenyl]methanesulfonamides and their use as cardiovascular agents
Novel N-[4-(aminosubstituted)phenyl]methanesulfonamides and their use as cardiovascular agents, especially as antiarrhythmic agents are described. Pharmaceutical formulations containing such compounds are also discussed.
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(2008/06/13)
Synthesis and Cardiac Electrophysiological Activity of Aryl-Substituted Derivatives of the Class III Antiarrhythmic Agent Sematilide. Potential Class I/III Agents
Twelve novel derivatives of the selective class III antiarrhythmic agent sematilide were prepared in an attempt to incorporate both class I and class III electrophysiological properties into a single molecule.Electrophysiological activity was determined b
Phillips, Gary B.,Morgan, Thomas K.,Nickisch, Klaus,Lind, Joan M.,Gomez, Robert P.,et al.
p. 627 - 633
(2007/10/02)
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