Palladium-catalyzed hydroxycarbonylation as the key step in the synthesis of a carbon-14 labeled Maxi-K channel blocker
Carbon-14 labeled sodium formate was utilized for the preparation of a radiolabeled tracer to support the development of a Maxi-K channel blocker. Key to the process was a palladium-catalyzed hydroxycarbonylation of a bromoarene for installation of the radiolabel. Copyright
Simeone, Joseph P.,Braun, Matthew P.,Liu, Luping,Natarajan, Swaminathan R.
p. 511 - 516
(2011/08/09)
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