Heterocyclization using phase transfer catalysis: A simple and convenient synthesis of 2-amino-1-aryl-5-oxo-4,5-dihydro-1H-pyrrole-3-carbonitriles
A simple and convenient synthesis of 2-amino-1-aryl-5-oxo-4,5-dihydro-1H-pyrrole-3-carbonitriles has been studied with and without phase transfer conditions. The best results were obtained using 18-crown-6 under solid-liquid phase transfer conditions in a
Dave,Parikh
p. 1301 - 1306
(2007/10/03)
Synthesis and Reactions of 2-Amino-1-aryl-5-oxo-Δ2-pyrroline-3-carbonitriles
The reaction of malononitrile with α-chloro acetanilides 1 in presence of potassium carbonate yields the 1-aryl-5-oxo-Δ2-pyrrolin-3-carbonitriles 2, in presence of triethylamine the 4,6-diamino-1-aryl-2-oxo-2,3-dihydropyrrolopyridin-5-ca
Schaefer, Harry,Gewald, Karl
p. 315 - 322
(2007/10/02)
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