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tert-Butyl 2-[4-(cyanoMethyl)phenoxy]acetate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 124499-21-4 Structure
  • Basic information

    1. Product Name: tert-Butyl 2-[4-(cyanoMethyl)phenoxy]acetate
    2. Synonyms: tert-Butyl 2-[4-(cyanoMethyl)phenoxy]acetate;(4-CYANOMETHYL-PHENOXY)-ACETIC ACID TERT-BUTYL ESTER
    3. CAS NO:124499-21-4
    4. Molecular Formula: C14H17NO3
    5. Molecular Weight: 247.28968
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 124499-21-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 366.6±22.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.095±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: tert-Butyl 2-[4-(cyanoMethyl)phenoxy]acetate(CAS DataBase Reference)
    10. NIST Chemistry Reference: tert-Butyl 2-[4-(cyanoMethyl)phenoxy]acetate(124499-21-4)
    11. EPA Substance Registry System: tert-Butyl 2-[4-(cyanoMethyl)phenoxy]acetate(124499-21-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 124499-21-4(Hazardous Substances Data)

124499-21-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 124499-21-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,4,4,9 and 9 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 124499-21:
(8*1)+(7*2)+(6*4)+(5*4)+(4*9)+(3*9)+(2*2)+(1*1)=134
134 % 10 = 4
So 124499-21-4 is a valid CAS Registry Number.

124499-21-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl 2-[4-(cyanomethyl)phenoxy]acetate

1.2 Other means of identification

Product number -
Other names p-(t-butoxycarbonylmethoxy)-phenylacetonitrile

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:124499-21-4 SDS

124499-21-4Relevant articles and documents

An Fc–Small Molecule Conjugate for Targeted Inhibition of the Adenosine 2A Receptor

Hsiao, Po-Yuan,Kalin, Jay H.,Sun, Im-Hong,Amin, Mohammed N.,Lo, Ying-Chun,Chiang, Meng-Jung,Giddens, John,Sysa-Shah, Polina,Gabrielson, Kathleen,Wang, Lai-Xi,Powell, Jonathan D.,Cole, Philip A.

, p. 1951 - 1960 (2016/10/24)

The adenosine A2A receptor (A2AR) is expressed in immune cells, as well as brain and heart tissue, and has been intensively studied as a therapeutic target for multiple disease indications. Inhibitors of the A2AR have the

Diagnostic uses of 2-substituted adenosine carboxamides

-

, (2008/06/13)

The present invention discloses a method for measuring myocardial function in a mammal in need of such measurement by: a) administering 2-substituted adenosine carboxamide derivatives at a dosage rate of less than 1 μg/kg/min, preferably between about 0.01 and 1 μg/kg/min; and then: b) performing a technique on the mammal to detect myocardial function. The method can be used to diagnose myocardial dysfunction by electrophysiologic analysis or by imaging the vasculature of the heart, especially under conditions that simulate stress.

2-(SUBSTITUTED AMINO) ADENOSINES AS ANTIHYPERTENSIVES

-

, (2008/06/13)

Disclosed are 2-substituted adenosine derivatives of the formula STR1 in which R represents a substituted amino grouping of the formula STR2 as defined herein; pharmaceutically acceptable ester derivatives thereof in which free hydroxy groups are esterified in the form of a pharmaceutically acceptable prodrug ester; and pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising said compounds; methods for their preparation; and their use in mammals as therapeutically effective adenosine-2 (A-2) agonists.

2-(Arylalkylamino)adenosin-5'-uronamides: A New Class of Highly Selective Adenosine A2 Receptor Ligands

Hutchison, Alan J.,Williams, Michael,Jesus, Reynalda, de,Yokoyama, Rina,Oei, Howard H.,et al.

, p. 1919 - 1924 (2007/10/02)

The synthesis and receptor-binding profiles at adenosine receptor subtypes for a series of 2-(arylalkylamino)adenosin-5'-uronamides is described.Halogenated 2-phenethylamino analogues such as 3e show greater than 200-fold selectivity for the A2 receptor s

2-substituted adenosine 5'-carboxamides as antihypertensive agents

-

, (2008/06/13)

The compounds of the formula I STR1 wherein R represents hydrogen or lower alkyl; R 1 represents C 3 -C 6 -cycloalkyl optionally substituted by lower alkyl, C 3 -C 6 -cycloalkyl-lower alkyl optionally substituted by lower alkyl, bicycloalkyl, bicycloalkyl-lower alkyl, aryl, aryl-lower alkyl, aryl-C 3 -C 6 -cycloalkyl, 9-fluorenyl, diaryl-lower alkyl, 9-fluorenyl-lower alkyl, cycloalkenyl-lower alkyl, bicycloalkenyl-lower alkyl, tetrahydropyranyl-lower alkyl, tetrahydrothiopyranyl-lower alkyl or adamantyl-lower alkyl; or R 1 represents a bicyclic benzo-fused 5- or 6-membered saturated carbocyclic radical or a benzo-fused 5- or 6-membered saturated heterocyclic radical containing a heteroatom selected from oxygen and sulfur which is directly attached to the fused benzene ring, any said bicyclic radical being unsubstituted or substituted on the benzo portion by lower alkyl, lower alkoxy, hydroxy, halogen or trifluoromethyl, or by a substituent -W-Z in which W represents a direct bond, lower alkylene, lower alkenylene, thio-lower alkylene or oxy-lower alkylene and Z represents cyano, carboxy or carboxy derivatized in the form of a pharmaceutically acceptable ester or amide, or R 1 represents any said bicyclic radical substituted-lower alkyl; or R 1 represents aryl-hydroxy-lower alkyl; R 2 represents hydrogen, lower alkyl or aryl-lower alkyl; R 3 represents hydrogen or hydroxy; R 4 represents hydrogen, lower alkyl, aryl-lower alkyl, C 3 -C 6 -cycloalkyl or hydroxy-lower alkyl; aryl represents an optionally substituted carbocyclic aromatic radical, being preferably 1- or 2-naphthyl, phenyl, or naphthyl or phenyl substituted by one to three of lower alkyl, lower alkoxy, hydroxy, halogen or trifluoromethyl, or naphthyl or phenyl substituted by a substitutent -W-Z in which W represents a direct bond, lower alkylene, lower alkenylene, thio-lower alkylene or oxy-lower alkylene and Z represents cyano, carboxy or carboxy derivatized in the form of a pharmaceutically acceptable ester or amide; or aryl represents a heterocyclic aromatic radical, being preferably pyridyl or thienyl, each optionally substituted as described above for phenyl; pharmaceutically acceptable ester derivatives thereof in which free hydroxy groups are esterified in the form of a pharmaceutically acceptable ester; and pharmaceutically acceptable salts thereof; their preparation; and their use as adenosine-2 receptor agonists are disclosed.

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