Improved palladium-catalysed synthesis of α-benzyl-β-keto esters
This paper describes the development of an imporved protocol for the synthesis of α-benzyl-β-keto esters from aryl bromides via Heck reaction. The use of this protocol to synthesise a variety of diverse α-benzyl-β-keto esters for use in the preparation of new pharmaceutical agents is demonstrated. Georg Thieme Verlag Stuttgart New York.
Bennett, Nicholas J.,Goldby, Anne,Pringle, Rachel
experimental part
p. 1688 - 1690
(2010/08/20)
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