High-throughput method for determining the enantioselectivity of enzyme-catalyzed hydroxylations based on mass spectrometry
(Chemical equation presented) Up to speed: An accurate, sensitive, high-throughput, and simple method for measuring the product ee value of enzyme-catalyzed hydroxylations (see scheme) is based on the use of enantiopure or enantioenriched deuterated substrates and mass spectrometric detection.
Chen, Yongzheng,Tang, Weng Lin,Mou, Jie,Li, Zhi
supporting information; experimental part
p. 5278 - 5283
(2010/10/19)
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