1246384-88-2Relevant articles and documents
Synthesis of novel 4-fluoro-2H-pyrazol-3-ylamines
Cocconcelli, Giuseppe,Ghiron, Chiara,Haydar, Simon,Micco, Iolanda,Zanaletti, Riccardo
experimental part, p. 2547 - 2555 (2010/09/18)
A new and efficient synthesis for the preparation of novel 4-fluoro-2H-pyrazol-3-ylamines is described. It involves the reaction of an acyl chloride with fluoroacetonitrile and sequential ring closure of the-fluoro-ketonitrile with hydrazine. Utilizing this synthetic protocol, we have synthesized a variety of 4-fluoro-2H-pyrazol-3-ylamines with different steric and electronic demands. Taylor & Francis Group, LLC.