RADIOIODINATION VIA VINYLSTANNYLATED ALKYLATING AGENTS
p-Toluenesulfonate esters of (E)- and (Z)-3-(tri-n-butylstannyl)-2-propen-1-ol readily react with nucleophiles to give vinylstannanes which are substrates for rapid, efficient and stereospecific radioiododestannylation at the no-carrier-added level.This general approach is illustrated by syntheses of iodinated spiperone analogs for studies of dopamine D2 receptors.
Musachio, John L.,Lever, John L.
p. 3613 - 3616
(2007/10/02)
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