- FATTY ACID SYNTHASE INHIBITORS
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This invention relates to novel spirocyclic piperidines according to Formula (I) which are inhibitors of fatty acid synthase (FAS), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the treatment of cancers.
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Page/Page column 74
(2014/01/18)
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- FATTY ACID SYNTHASE INHIBITORS
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This invention relates to spirocyclic piperidines according to Formula (I) and the use of spirocyclic piperidines for the modulation, notably the inhibition of the activity or function of fatty acid synthase (FAS). Suitably, the present invention relates to the use of spirocyclic piperidines in the treatment of cancer.
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Page/Page column 103
(2013/03/26)
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- FATTY ACID SYNTHASE INHIBITORS
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Disclosed are compounds having Formula (I), wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, Y, m, and n are defined herein and methods of using the same.
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Page/Page column 61; 62
(2014/01/07)
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- FATTY ACID SYNTHASE INHIBITORS
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Disclosed are compounds having Formula (I), or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R5, R6, R7, R8, R8a, R9 Y, and m are defined herein and methods of using the same.
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Page/Page column 50; 65
(2013/04/24)
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