SIMPLE AND CONDENSED &β-LACTAMS, 10. HYDANTOINS, THIOHYDANTOINS, CLYCOCYAMIDINES, 45. NOVEL SEMISYNTHETIC CEPHALOSPORINS. DITHIOHYDANTOIN DERIVATIVES FOR THE MODIFICATION OF THE SIDE CHAIN IN POSITION 3
Some novel semisynthetic cephalosporins (9-12) were synthesized.For the modification of the side chain in position 3, S-monosubstituted-5,5-dimethyl-dithiohydantoins (2,3,5) prepared by selective alkylation and dealkylation, were used.