Straightforward preparation of enantiopure 3-amino-4,4-dimethylpyrrolidin- 2-one and its derivatives
An easy access to both enantiomers of 3-amino- and 3-(dimethylamino)-4,4- dimethylpyrrolidin-2-one from rac-pantolactam using (R)-α- methylbenzylamine as a chiral auxiliary is described.
Camps, Pelayo,Munoz-Torrero, Diego,Rull, Jordi,Mayoral, Jose Antonio,Calvet, Teresa,Font-Bardia, Merc
experimental part
p. 2124 - 2135
(2010/10/03)
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