Novel 16-homo-piperidino-androstane derivatives and processes for their preparation
The invention relates to compounds having the formula: wherein R1 is H or an acyl group having 1-12 carbon atoms,R2 and R3 are an alkyl or aralkyl group having 1-12 car-bon atoms, or when taken together form with the nitrogen atom a heterocyclic amino radical; and R4 is H or an acyl group having 1-12 carbon atoms; and mono- or bisquaternary ammonium compounds thereof and acid addition salts of the non- or mono-quaternary ammonium compounds and to a process for preparing these compounds. The compounds are neuromuscular blocking agents with a fast onset and a short duration and which exhibit no or hardly any blood pressure drop.
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(2008/06/13)
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Get Best Price for124898-74-4(2beta,3alpha,5alpha,8xi,9xi,14xi,16beta,17beta)-3-(acetyloxy)-17-(butanoyloxy)-16-(1-methylazepanium-1-yl)-2-(piperidin-1-yl)androstane bromide